Cytokine Preconditioning Promotes Codifferentiation of Human Fetal Liver CD133 ⁺ Stem Cells Into Angiomyogenic Tissue

Abstract

CD133 defines a population of human fetal liver cells capable of differentiating into both angiogenic and myogenic cells. Preconditioning of these CD133+ cells with VEGF165 and BDNF enhances the angiomyogenesis. CD133+ fetal liver cells ultimately may be used for therapeutic angiomyogenesis.