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Dissociation of FKBP12.6 from ryanodine receptor type 2 is regulated by cyclic ADP-ribose but not β-adrenergic stimulation in mouse cardiomyocytes

DOIFull Paper Access

44

Citations

41

References

2009

Year

Xu Zhang, Yvonne N. Tallini, Zheng Chen, Lu Gan, Bin Wei, Robert Doran, Lin Miao, Hong‐Bo Xin, Michael I. Kotlikoff, Guangju Ji
Cardiovascular Research

Abstract

Our data demonstrate that dissociation of FKBP12.6 from the RYR2 complex does not play a significant role in beta-adrenergic-stimulated Ca(2+) release in heart cells, whereas this mechanism does underlie the action of cADPR.

References

YearCitations

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