A Mutational Analysis of Residues Essential for Ligand Recognition at the Human P2Y1 Receptor

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

Michael J. Berridge, R. M. C. Dawson, C. Peter Downes et al. · Biochemical Journal · 1983 · 2K citations · Full text

Life Sciences, Biochemistry, Entomology +14

The probable arrangement of the helices in G protein‐coupled receptors.

J.M. Baldwin · The EMBO Journal · 1993 · 979 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.

Hiroto Okayama, P Berg · Molecular and Cellular Biology · 1983 · 935 citations

Life Sciences, Molecular Biology, Molecular Genetics +15

[71] Use of eukaryotic expression technology in the functional analysis of cloned genes

Bryan R. Cullen · Methods in enzymology on CD-ROM/Methods in enzymology · 1987 · 836 citations

Life Sciences, Genetics, Molecular Biology +14