Journal of Veterinary Medical Science · 2011 · 46 citations · 24 references
Veterinary MedicineImmunologyVeterinary PathologyImmunopathologySmall Animal MedicineTumor PathologyColonic DisordersGastrointestinal ImmunologyGastrointestinal InflammationInflammatory Bowel DiseaseInflammatory LesionsVeterinary ImmunologyColonic InflammationColonic PolypsGastrointestinal PolypsImmunosuppressive Drug TherapyMucosal PolypsRetrospective Case StudySystemic Immunosuppressive Therapy
Medical records of dogs with colorectal polyps were retrospectively reviewed, and clinical presentation of inflammatory colorectal polyps in miniature dachshunds was evaluated. Of 33 dogs found to have colorectal polyps, miniature dachshunds were markedly over-represented with 16 dogs (48%), of which 12 (75%) were found to have inflammatory polyps. Multiple polyps localized between the rectum and the descending colon was the most common finding in miniature dachshunds with inflammatory polyps. Twenty dogs (80%) out of 25 miniature dachshunds with inflammatory colorectal polyps responded to immunosuppressive therapy using prednisolone and cyclosporine. The results of this study indicate that miniature dachshunds are predisposed to develop inflammatory colorectal multiple polyps, for which immunosuppressive therapy may be a treatment option.
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Inflammatory Bowel Disease as a Risk Factor for Colorectal Cancer
Milan Lukáš · Digestive Diseases · 2010 · 97 citations
Medicine, Oncology, Gastroenterology +14
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