Epidemiology and Infection · 2011 · 10 citations · 18 references
MedicineInfectious Disease ControlInfectious DiseasesCommunicable Disease ControlDisease PreventionEpidemiologyControl Measure ImplementationDisease ControlDisease SpreadInfectious Disease PreventionOutbreak ControlVaccinationChildhood Infectious Disease PreventionHigh-risk BehaviorHygieneInfection Control MeasuresInfluenza Infection ControlPediatric Influenza EpidemiologySchool Disease SurveillanceSchool-based Transmission
A pandemic influenza A(H1N1) 2009 outbreak in a summer school affected 117/276 (42%) students. Residential social contact was associated with risk of infection, and there was no evidence for transmission associated with the classroom setting. Although the summer school had new admissions each week, which provided susceptible students the outbreak was controlled using routine infection control measures (isolation of cases, basic hygiene measures and avoidance of particularly high-risk social events) and prompt treatment of cases. This was in the absence of chemoprophylaxis or vaccination and without altering the basic educational activities of the school. Modelling of the outbreak allowed estimation of the impact of interventions on transmission. These models and follow-up surveillance supported the effectiveness of routine infection control measures to stop the spread of influenza even in this high-risk setting for transmission.
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A Simplex Method for Function Minimization
J. A. Nelder, R. Mead · The Computer Journal · 1965 · 28.9K citations
Pandemic Potential of a Strain of Influenza A (H1N1): Early Findings
Christophe Fraser, Christl A. Donnelly, Simon Cauchemez et al. · Science · 2009 · 2K citations · Full text
Simon Cauchemez, Achuyt Bhattarai, Tiffany Marchbanks et al. · Proceedings of the National Academy of Sciences · 2011 · 389 citations · Full text