Publication | Open Access
Synthesis, structure and biological evaluation of bis salicylaldehyde-4(N)-ethylthiosemicarbazone ruthenium(<scp>iii</scp>) triphenylphosphine
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Citations
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References
2010
Year
Bioorganic ChemistryOrganic ChemistryChemistryHeterocycle ChemistryChemical BiologyPharmaceutical ChemistryMedicinal ChemistryDpph RadicalBis Salicylaldehyde-4Anti-cancer Agent-Ethylthiosemicarbazone RutheniumBiochemistryRadical (Chemistry)PharmacologyNatural Product SynthesisBiomolecular EngineeringNatural SciencesMedicineSynthetic ChemistryDrug Discovery
Bis salicylaldehyde-4(N)-ethylthiosemicarbazone ruthenium(iii) triphenylphosphine [Ru(Sal-etsc)(H-Sal-etsc)(PPh(3))] was synthesized and structurally characterized by spectral and X-ray crystallographic studies and it showed 100% inhibition on the DPPH radical. It also exhibited a significant lymphocyte activity and inhibitory effect on the lung carcinoma A549 cell.
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