The 677 C/T MTHFR Polymorphism is Associated with Essential Hypertension, Coronary Artery Disease, and Higher Homocysteine Levels

Total Plasma Homocysteine and Cardiovascular Risk Profile

Ottar Nygård, Stein Emil Vollset, Helga Refsum et al. · JAMA · 1995 · 1K citations

Medicine, Geriatric Medicine, Aging +7

Homocyst(e)ine Decreases Bioavailable Nitric Oxide by a Mechanism Involving Glutathione Peroxidase

Gilbert R. Upchurch, George N. Welch, Attila J. Fabian et al. · Journal of Biological Chemistry · 1997 · 672 citations · Full text

Life Sciences, Biochemistry, Physiology +17

Decreased Rate of Coronary Restenosis after Lowering of Plasma Homocysteine Levels

Guido Schnyder, Marco Roffi, Riccardo Pin et al. · New England Journal of Medicine · 2001 · 532 citations · Full text

Medicine, Cardiology, Physiology +14

Methylenetetrahydrofolate Reductase Polymorphism, Plasma Folate, Homocysteine, and Risk of Myocardial Infarction in US Physicians

Jing Ma, Meir J. Stampfer, Charles H. Hennekens et al. · Circulation · 1996 · 487 citations · Full text

Medicine, Genetics, Molecular Genetics +15

Effect of Homocysteine-Lowering Therapy With Folic Acid, Vitamin B₁₂, and Vitamin B₆on Clinical Outcome After Percutaneous Coronary Intervention

Guido Schnyder, Marco Roffi, Yvonne Flammer et al. · JAMA · 2002 · 381 citations

Medicine, Cardiology, Interventional Cardiology +16