Publication | Open Access
Formal asymptotic limit of a diffuse-interface tumor-growth model
74
Citations
29
References
2014
Year
Numerical AnalysisEngineeringFree Boundary ProblemDiffusion ProcessFormal Asymptotic LimitSingular LimitGeometric Singular Perturbation TheoryNonlinear Hyperbolic ProblemBiomedical ModelingDiffuse-interface Tumor-growth ModelIntegrable SystemCancer GrowthReaction TermBiophysicsNumerical Method For Partial Differential EquationMultiscale Modeling
We consider a diffuse-interface tumor-growth model which has the form of a phase-field system. We characterize the singular limit of this problem. More precisely, we formally prove that as the coefficient of the reaction term tends to infinity, the solution converges to the solution of a novel free boundary problem. We present numerical simulations which illustrate the convergence of the diffuse-interface model to the identified sharp-interface limit.
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