Human Nocturnal Frontal Lobe Epilepsy: Pharmocogenomic Profiles of Pathogenic Nicotinic Acetylcholine Receptor β-Subunit Mutations outside the Ion Channel Pore

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Owen P. Hamill, Alain Marty, Erwin Neher et al. · Pflügers Archiv - European Journal of Physiology · 1981 · 18.5K citations

Natural Sciences, Biophysics, Cell Biology +16

Incidence of Epilepsy and Unprovoked Seizures in Rochester, Minnesota: 1935–1984

W. Allen Hauser, John F. Annegers, Leonard T. Kurland · Epilepsia · 1993 · 2.1K citations

Medicine, Neurology, Epilepsy +8

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

Philippe Séguéla, Jacques I. Wadiche, Kelly Dineley‐Miller et al. · Journal of Neuroscience · 1993 · 1.5K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Structure and gating mechanism of the acetylcholine receptor pore

Atsuo Miyazawa, Yoshinori Fujiyoshi, Nigel Unwin · Nature · 2003 · 1.3K citations

Life Sciences, Biochemistry, Biophysics +12

A missense mutation in the neuronal nicotinic acetylcholine receptor α4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy

Ortrud K. Steinlein, John C. Mulley, Peter Propping et al. · Nature Genetics · 1995 · 1.1K citations

Life Sciences, Neurology, Neuroscience +12