Liver Fibrosis in Chronic Hepatitis C Virus Infection: Differentiating Minimal from Intermediate Fibrosis with Perfusion CT

Abstract

The results of this study show that perfusion changes occur early during fibrosis in chronic HCV infection and can be detected with perfusion CT. Perfusion CT may help to discriminate minimal from intermediate fibrosis. Mean transit time appears to be the most promising perfusion parameter for differentiating between fibrosis stages, although the large amount of overlap in the measured parameters limits the clinical utility of this test at present.