Elevations in vascular markers and eosinophils in chronic spontaneous urticarial weals with low‐level persistence in uninvolved skin

Abstract

Increased vascular markers together with eosinophil and neutrophil infiltration are features of lesional skin in CSU and might contribute to tissue oedema. Eosinophils and microvascular changes persist in uninvolved skin, which, together with increased mast cells, suggests that nonlesional skin is primed for further wealing.