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Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease

Chromosome 1P13.3Allelic VariantGenetic DeterminantCellular Ldl-uptakeCardiovascular DiseaseGeneticsHuman PolymorphismVascular BiologyMolecular GeneticsSystems BiologyMedicineAtherosclerosisCardiovascular GeneticsCoronary Artery Disease