Pravastatin Inhibits the Rho/CCN2/Extracellular Matrix Cascade in Human Fibrosis Explants and Improves Radiation-Induced Intestinal Fibrosis in Rats - Concepedia

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Pravastatin Inhibits the Rho/CCN2/Extracellular Matrix Cascade in Human Fibrosis Explants and Improves Radiation-Induced Intestinal Fibrosis in Rats

133

Citations

26

References

2007

Year

Valérie Haydont, C. Bourgier, Marc Pocard, Antoine Lusinchi, J. Aigueperse, Denis Mathé, Jean Bourhis, Marie‐Catherine Vozenin

Clinical Cancer Research

Abstract

Targeting established fibrosis with pravastatin is an efficient and safe antifibrotic strategy in radiation-induced enteropathy, and is easily transferable into the clinic.

References

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