Double Elimination Protocol for Access to Pyridine-Containing Arylene–Ethynylenes

Abstract

Abstract The arylene–ethynylene arrays involving pyridine were constructed successfully by taking advantage of double elimination reaction of β-substituted sulfones (sulfoximines) which are easily accessible from arylmethyl sulfones (sulfoximines) and aromatic aldehydes. This protocol was utilized for synthesis of an enantiopure arylene–ethynylene framework bearing a binaphthyl stereogenic core.