Detection and Measurement of Urinary 2-Hydroxyestradiol 17-Sulfate, a Potential Placental Antioxidant during Pregnancy

Abstract

RIA can be used to measure urinary 2-OH-ES during pregnancy. The increase in urinary 2-OH-ES during gestation, its decrease after delivery, and the lower values in preeclampsia are consistent with a role of 2-OH-ES as a placental antioxidant.