Analytical Chemistry · 2011 · 192 citations · 36 references
PharmacyCell BiologyMolecular BiologyMagnetic MaterialsSeparation ProcessesSeparation ScienceCell IsolationCell SeparationImmunomagnetic SeparationMagnetic MethodsMagnetic SeparationPermanent MagnetsEnrichment Of Rare CellsImmunomagnetic PurificationMagnetic Cell SeparationMicrobead SeparationRare Cell AnalysisRare Cell EnrichmentRare Cell IsolationRare-earth Permanent Magnets
The separation and or isolation of rare cells using magnetic forces are commonly used and growing in use ranging from simple sample prep for further studies to a FDA approved, clinical diagnostic test. This growth is the result of both the demand to obtain homogeneous rare cells for molecular analysis and the dramatic increases in the power of permanent magnets that even allow the separation of some unlabeled cells based on intrinsic magnetic moments, such as malaria parasite-infected red blood cells.
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Applications of magnetic nanoparticles in biomedicine
Quentin A. Pankhurst, Joan Connolly, Stephen Jones et al. · Journal of Physics D Applied Physics · 2003 · 5.8K citations
Detection of Mutations in <i>EGFR</i> in Circulating Lung-Cancer Cells
Shyamala Maheswaran, Lecia V. Sequist, Sunitha Nagrath et al. · New England Journal of Medicine · 2008 · 1.6K citations · Full text