Autoregulation by Eicosanoids of Human Kupffer Cell Secretory Products A Study of Interleukin-1, Interleukin-6, Tumor Necrosis Factor-α, Transforming Growth Factor-β, and Nitric Oxide

Abstract

Although many functional features are shared by rat and human KCs, significant differences do exist. Such discrepancies reinforce the need to proceed with caution when generalizing from the results obtained in other species to human physiology.