(4<i>S</i>)-4-(3-¹⁸F-Fluoropropyl)-l-Glutamate for Imaging of x_C^¯ Transporter Activity in Hepatocellular Carcinoma Using PET: Preclinical and Exploratory Clinical Studies

Abstract

(18)F-FSPG was successfully translated from preclinical evaluation into patients with HCC. (18)F-FSPG may be a promising tumor PET agent with a high cancer detection rate in patients with HCC.