Inhaled corticosteroid reduced <i>lamina reticularis</i> of the basement membrane by modulation of insulin‐like growth factor (IGF)‐I expression in bronchial asthma

Abstract

These results suggest that corticosteroid treatment in asthma can reduce the lamina reticular thickness by modulation of IGF-I expression with consequent inhibition of the airway infiltration by inflammatory cells, and therefore may help to prevent remodelling of the airways.