Publication | Closed Access
Synthesis and Biological Properties of Some 3‐Heterocyclic Substituted Coumarins
28
Citations
7
References
1981
Year
Medicinal ChemistryDerivative (Chemistry)Antifungal AgentPara PositionAntifungal AgentsNitro GroupMedicineBiological PropertiesOrganic ChemistryAntimicrobial ChemotherapyMicrobiologyHeterocycle ChemistryAntimicrobial CompoundPharmacologyFused ThiazolesPharmaceutical ChemistryDrug Discovery
Abstract 2‐Mercaptobenzimidazoles and 3‐phenyl‐5‐mercapto‐ s ‐triazoles have been reacted with 3‐(bromoacetyl)coumarin to get the fused thiazoles. Antiinflammatory studies indicate that the introduction of a nitro group at the para position of the phenyl ring enhances the activity to a great extent. Antibacterial and antifungal activities were also tested.
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