Determination of Amino Acid Enantiopurity and Absolute Configuration: Synergism between Configurationally Labile Metal‐Based Receptors and Dynamic Covalent Interactions

Abstract

Reliable determination of the enantiomeric excess of free amino acids can be obtained by measuring the induced circular dichroism of a multicomponent assembly formed by a modified tris(2-pyridylmethyl)amine ligand, a zinc salt, and the amino acid of interest. The systems furnish reliable information for all natural amino acids.