Concepedia

CD8 T Cell-Specific Downregulation of Histone Hyperacetylation and Gene Activation of the IL-4 Gene Locus by ROG, Repressor of GATA

Miyuki Omori, Masakatsu Yamashita, Masamichi Inami, Maki Ukai‐Tadenuma, Motoko Y. Kimura, Yukiko Nigo, Hiroyuki Hosokawa, Akihiro Hasegawa, Masaru Taniguchi, Toshinori Nakayama

Immunity · 2003 · 83 citations · 36 references

Concepts

Life SciencesImmunologyMolecular BiologyEpigeneticsGene ExpressionTranscriptional RegulationChromatinHelper T Cell SubsetsHistone ModificationsImmune Gene RegulationT Cell BiologyTranscriptional SilencingCd8 Positive T Cell ResponsesCytotoxic T Lymphocyte - Associated Protein 4 PathwayCytotoxic T Lymphocyte-associated Protein 4 PathwayEpigenetic Gene ActivationEpigenetic Regulation Of T Cell DifferentiationGene Activation MechanismsT Cell Epigenetics

References

36

The language of covalent histone modifications

Brian D. Strahl, C. David Allis · Nature · 2000 · 8.6K citations

Life Sciences, Biochemistry, Molecular Biology +12

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

Susanne J. Szabo, Sean Kim, Gina L. Costa et al. · Cell · 2000 · 3.5K citations · Full text

Life Sciences, Immunology, Molecular Biology +13

The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

Wei-ping Zheng, Richard A. Flavell · Cell · 1997 · 2.4K citations · Full text

Life Sciences, Genetics, Immunology +17

Essential role of Stat6 in IL-4 signalling

Takashi Tanaka, Wei Shi, Makoto Matsumoto et al. · Nature · 1996 · 1.6K citations · Full text

Life Sciences, Immunology, Molecular Biology +11

Helper T Cell Differentiation Is Controlled by the Cell Cycle

Jennifer J. Bird, Daniel R. Brown, Alan C. Mullen et al. · Immunity · 1998 · 840 citations · Full text

Life Sciences, Cell Biology, Immunology +14