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On the Xq13 Breakpoint: Clinical and Cytogenetic Observations in a Patient with Acute Myelogenous Leukemia
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1983
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CytogeneticsMixed-phenotype Acute LeukemiaGeneticsPathologyCytogenetic ObservationsEpigeneticsAcute Myelogenous LeukemiaAcute LeukemiaMyeloid NeoplasiaHematological MalignancyXq13 BreakpointOncologyHematologyRadiation OncologyCancer ResearchHealth SciencesCytogenetic StudyChromatinXq13 BreakpointsMalignant Blood DisorderAdult T-cell Leukemia-lymphomaMedicine
Cytogenetic study in a case of acute myelogenous leukemia revealed the presence of two identical dicentric marker chromosomes derived from an X with Xq13 breakpoints. Clinical and cytochemical findings suggest that the patient was affected by idiopathic acquired sideroblastic anemia before the acute leukemia.