A new route to functionalised π-allyltricarbonyliron lactam complexes from aziridines and their use in stereoselective synthesis and oxidative conversion to β-lactams

Abstract

Aziridinyl enones can be converted in good yield into π-allyltricarbonyliron lactam complexes bearing ketone functionality in the side chain; addition of a variety of nucleophiles into the side chains of these complexes proceeds in good yield and excellent (>95%) de to afford secondary and tertiary alcohols which on treatment with trimethylamine N-oxide form the corresponding β-lactams in good yield.