Rapid and substantial lowering of human serum cholesterol by mevinolin (MK-803), an inhibitor of hydroxymethylglutaryl-coenzyme a reductase

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

Alfred W. Alberts, J Chen, G. W. Kuron et al. · Proceedings of the National Academy of Sciences · 1980 · 1.6K citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Predisposition to Atherosclerosis in the Head, Heart, and Legs

Tavia Gordon · JAMA · 1972 · 344 citations

Medicine, Cardiology, Clinical Cardiology +14

Inhibitory Effects on Lipid Metabolismn in Cultured Cells of ML‐236B, a Potent Inhibitor of 3‐Hydroxt‐3‐methylglutaryl‐Cornzyme‐A Reductase

Osoa KANEKO, Hazama-Shimada Yoko, Akira Endo · European Journal of Biochemistry · 1978 · 248 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Therapeutic effects of ML-236B in primary hypercholesterolemia

Akira Yamamoto, Hiroshi Sudo, Akira Endo · Atherosclerosis · 1980 · 232 citations

Medicine, Pharmacology, Pharmacotherapy +15

Studies of Cholesterol Biosynthesis

Joel Avigan, Daniel Steinberg, Hugh E. Vroman et al. · Journal of Biological Chemistry · 1960 · 197 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11