Extrapulmonary Manifestations of Bronchogenic Carcinoma

Abstract

CANCER is a systemic disorder as well as a local derangement of tissue growth. Generalized effects of a malignant tumor often occur in the absence of any demonstrable spread of the disease, even though recent studies have shown that neoplastic cells can be found floating free in the blood of many such patients.1 Bronchogenic carcinoma, the most frequent malignant tumor in the United States, may become clinically manifest through symptoms related to the local lesion, symptoms secondary to specific metastases or symptoms due to the systemic effects of the tumor. The local effects are largely those of irritation (cough), ulceration . . .