Structural and Functional Abnormalities of Retinal Ganglion Cells Measured In Vivo at the Onset of Optic Nerve Head Surface Change in Experimental Glaucoma

Abstract

These results support the hypothesis that during the course of glaucomatous neurodegeneration, axonal cytoskeletal and retinal ganglion cell functional abnormalities exist before thinning of peripapillary RNFL axon bundles begins.