PREDICTION AND PREVENTION OF FISTULAE AFTER MAJOR HEAD AND NECK SURGERY A PRELIMINARY REPORT

Abstract

A method of checking the integrity of mucosal repair after head and neck surgery using wound amylase levels is described. A low wound amylase concentration allows early resumption of oral intake; an increasing amylase concentration is a strong predictor of subsequent wound breakdown and fistula formation. A regimen has been developed which has prevented fistulae from developing in the small number of patients studied thus far.