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Life SciencesBiochemistryMolecular BiologyCell SignalingProtein-protein InteractionsSignal TransductionCell Signaling NetworksG Protein-coupled Receptor SignalingSmall Gtpase SignalingG Protein Subunit ActivationG-protein-coupled ReceptorsGtp Hydrolysis RegulationHeterotrimeric G Protein Signaling
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Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
David E. Coleman, Albert M. Berghuis, E Lee et al. · Science · 1994 · 832 citations
Structural determinants for activation of the α-subunit of a heterotrimeric G protein
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