Concepedia

Tissue-specific expression of a BAC transgene targeted to the Hprt locus in mouse embryonic stem cells

Jason D. Heaney, Ashley N. Rettew, Sarah K. Bronson

Genomics · 2004 · 38 citations · 50 references

Concepts

Life SciencesGeneticsMolecular GeneticsCell DifferentiationGene ExpressionStem Cell BiologyEmbryonic Stem CellsStem Cell DifferentiationTransgene DesignTransgene Expression ControlEmbryonic Stem Cell Gene TargetingEmbryonic Stem Cell TargetingEmbryonic Stem Cell-mediated Gene TargetingMouse Embryonic Stem CellsStem Cell Gene RegulationTissue-specific ExpressionTissue-specific Expression AnalysisTissue-specific Expression Vectors

References

50

Increased bone formation in osteocalcin-deficient mice

Patricia Ducy, Christelle Desbois, Brendan F. Boyce et al. · Nature · 1996 · 1.7K citations · Full text

Medicine, Orthopedic Surgery, Bone Metabolism +12

HPRT-deficient (Lesch–Nyhan) mouse embryos derived from germline colonization by cultured cells

Martin Hooper, Kate Hardy, Alan H. Handyside et al. · Nature · 1987 · 1.2K citations

Life Sciences, Developmental Biology, Genetics +16

A new logic for DNA engineering using recombination in Escherichia coli

Youming Zhang, Frank Buchholz, Joep P. P. Muyrers et al. · Nature Genetics · 1998 · 1.2K citations

Life Sciences, Biotechnology, Molecular Biology +16

A Highly Efficient Escherichia coli-Based Chromosome Engineering System Adapted for Recombinogenic Targeting and Subcloning of BAC DNA

E-Chiang Lee, Daiguan Yu, Jason Velasco et al. · Genomics · 2001 · 1.2K citations

Life Sciences, Biotechnology, Genetics +14

Rapid modification of bacterial artificial chromosomes by ET- recombination

Joep P. P. Muyrers · Nucleic Acids Research · 1999 · 537 citations · Full text

Life Sciences, Biotechnology, Genetics +17