Regulation of bone metabolism in immunosuppressant (FK506)-treated rats

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Jun S. Liu, Jesse D. Farmer, Willam S. Lane et al. · Cell · 1991 · 4.1K citations

Protein Function, Signal Transduction, Biochemistry +9

A COMPARISON OF TACROLIMUS (FK506) AND CYCLOSPORINE FOR IMMUNOSUPPRESSION AFTER CADAVERIC RENAL TRANSPLANTATION1

John D. Pirsch, Joshua Miller, Mark H. Deierhoi et al. · Transplantation · 1997 · 1.1K citations

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

Stephen J. O’Keefe, Jun‐ichi Tamura, Randall L. Kincaid et al. · Nature · 1992 · 854 citations

Inflammation, Csa-sensitive Activation, Cytokine +10

Frequency and predictors of osteoporotic fractures after cardiac or liver transplantation: a follow-up study

G. Leidig‐Bruckner, Stefanie Hosch, Petroula Dodidou et al. · The Lancet · 2001 · 267 citations

Skeletal Trauma, Transplantation Surgery, Bone Disease +9

THE DELETERIOUS EFFECTS OF LONG-TERM CYCLOSPORINE A, CYCLOSPORINE G, AND FK506 ON BONE MINERAL METABOLISM IN VIVO

Mirjana Cvetković, Gary N. Mann, David F. Romero et al. · Transplantation · 1994 · 250 citations

Animal Physiology, Cyclosporine G, Bone Health +15