Bioscience Biotechnology and Biochemistry · 2000 · 20 citations · 8 references
PharmacyMedicinal ChemistryPharmacologyDrug DiscoveryOrganic ChemistryStructure-activity RelationshipsAromatic PlantsMedicinal PlantsMetabolite IdentificationNatural Product Drug DiscoveryPlant Natural Product BiosynthesisSteroid StructureMedicinal Aromatic PlantsPlant-derived Natural ProductsTerpene Compounds
A novel monoterpenoid-derived metabolite, paeonilide, was isolated from the roots of Paeonia delavayi. Its structure was established by a combination of spectroscopic and X-ray crystallographic analyses. It showed an anti-PAF effect with an IC50 value of ca. 8 microg/ml.
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New bioactive monoterpene glycosides from paeoniae radix.
Nobutoshi Murakami, Masami SAKA, Hiromi Shimada et al. · Chemical and Pharmaceutical Bulletin · 1996 · 60 citations · Full text
Paeonilactone-A, -B, and -C, new monoterpenoids from paeony root
Toshimitsu Hayashi, Takako Shinbo, Mineo Shimizu et al. · Tetrahedron Letters · 1985 · 58 citations
Lactiflorin, a monoterpene glycoside from paeony root
Jin Yu, John A. Elix, Magdy N. Iskander · Phytochemistry · 1990 · 34 citations