Publication | Closed Access
Chiral Brønsted Acid Catalyzed Enantioselective Hydrophosphonylation of Imines: Asymmetric Synthesis of α-Amino Phosphonates
288
Citations
8
References
2005
Year
Room Temperatureα-Amino PhosphonatesAlpha-amino PhosphonatesEngineeringBiochemistryNatural SciencesAsymmetric SynthesisOrganic ChemistryChiral Brønsted AcidCatalysisStereoselective SynthesisChemistryAsymmetric CatalysisChemical DerivativeSynthetic ChemistryEnantioselective SynthesisBiomolecular Engineering
[reaction: see text] A cyclic phosphoric acid derivative, derived from (R)-BINOL, was used as a chiral Brønsted acid (10 mol %) in hydrophosphonylation of aldimines with diisopropyl phosphite at room temperature. Alpha-amino phosphonates were obtained with good to high enantioselectivities.
| Year | Citations | |
|---|---|---|
Page 1
Page 1