Elasticity of ``Fuzzy'' Biomembranes

Abstract

Sensitive micropipet methods have been used to measure the elastic stretch modulus and bending rigidity of biomembranes studded with water-soluble polymers. The fully extended lengths of the chemically grafted chains ranged from $10--50\ifmmode\times\else\texttimes\fi{}$ the length of the embedding membrane lipid. Concentrations of the polymer were varied from $1--10\ifmmode\times\else\texttimes\fi{}$ the surface density needed for isolated chains to touch, nominally satisfying the scaling theory requirement for semidilute brushes. Over this range, the membrane stretch modulus was unchanged by the polymer layers, but the bending rigidity increased by as much as ${10k}_{B}T$. Surprisingly, the increase in rigidity deviated significantly from scaling theory predictions, revealing a large marginal brush regime between dilute mushrooms and a semidilute brush.