Neutral endopeptidase 24.11 inhibition may not exhibit beneficial haemodynamic effects in patients with congestive heart failure

Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure

Wolfgang Kiowski, J Kim, Erwin Oechslin et al. · The Lancet · 1995 · 573 citations

Life Sciences, Cardiology, Physiology +11

Candoxatril, a neutral endopeptidase inhibitor

Elizabeth G. Bevan, John Connell, Jacqueline Doyle et al. · Journal of Hypertension · 1992 · 175 citations

Medicine, Pharmacology, Pharmacotherapy +16

Chronic inhibition of endopeptidase 24.11 in essential hypertension: evidence for enhanced atrial natriuretic peptide and angiotensin II

Mark Richards, Gary Wittert, Ian Crozier et al. · Journal of Hypertension · 1993 · 147 citations

Medicine, Cardiology, Pharmacology +17

Protection of atrial natriuretic factor against degradation: diuretic and natriuretic responses after in vivo inhibition of enkephalinase (EC 3.4.24.11) by acetorphan.

Claude P. Gros, Anny Souque, J. Schwartz et al. · Proceedings of the National Academy of Sciences · 1989 · 124 citations · Full text

Medicine, Cardiology, Pharmacology +9

Neurohormonal inhibition and hemodynamic unloading during prolonged inhibition of ANF degradation in patients with severe chronic heart failure.

Thomas Münzel, Stephan Kurz, J. Holtz et al. · Circulation · 1992 · 85 citations · Full text

Medicine, Cardiology, Pharmacology +12