PubMed · 2010 · 11 citations · 23 references
MedicineGeriatric MedicineRadiologyGeriatricsRenal PathologyVascular SurgeryRenal Cystic DiseasesRenal DiseaseCardiovascular SurgeryMedical Chart ReviewPreoperative Imaging EvaluationThoracic Aortic Aneurysm SurgeryUnivariate Analysis
OBJECTIVE: The aim of this study is to investigate the positive association between the presence of renal cysts and AAA. PATIENTS AND METHODS: A retrospective chart review on the clinical data of 396 consecutive patients, who underwent CT scans for preoperative evaluation of thoracic and cardiovascular surgery in Sapporo Medical University from the period of January 2007 to December 2008, was conducted. RESULTS: When comparing patients with renal cysts (n = 164) to those without (n = 233), there was a statistically significant difference between the presence of renal cysts and male gender (p = 0.007), hypertension (p = 0.003), and AAA (p < 0.001) on univariate analysis. In addition, when comparing patients with AAA to those without, although COPD but not AAA was associated with renal cysts in less than 65 years old, the presence of renal cysts was the strongest association with AAA among patients belonging to the 65 to 74 years old group and over 75 years old group on multivariate analysis. CONCLUSIONS: There is a statistically higher incidence of renal cysts in patients with AAA compared to patients without AAA in the group of elder cardiovascular patients. It is likely that AAA and renal cysts share a common pathogenesis.
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Robert Pyo, Jason K. Lee, J. Michael Shipley et al. · Journal of Clinical Investigation · 2000 · 827 citations · Full text
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Human abdominal aortic aneurysms. Immunophenotypic analysis suggesting an immune-mediated response.
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