Angewandte Chemie International Edition · 2010 · 285 citations · 38 references
Enantioselective SynthesisChiral FlpsEngineeringNatural SciencesSubsequent FrustrationOrganic ChemistryOrganometallic CatalysisCatalysisStereoselective SynthesisHydrogenQuantum ChemistryChemistryMolecular CatalysisAsymmetric CatalysisLewis PairsEnantioselective HydrogenationBiomolecular Engineering
No subsequent frustration: Frustrated Lewis pairs (FLPs) have been recently introduced as an unprecedented possibility to activate hydrogen. On the basis of this concept the first example of highly enantioselective catalytic hydrogenation of imines using chiral FLPs has been demonstrated (see scheme).
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Reversible, Metal-Free Hydrogen Activation
Gregory C. Welch, Ronan R. San Juan, Jason D. Masuda et al. · Science · 2006 · 2.1K citations