Concepedia

Effect of surface chemistry on nanoparticle interaction with gastrointestinal mucus and distribution in the gastrointestinal tract following oral and rectal administration in the mouse

Katharina Maisel, Laura M. Ensign, Mihika Reddy, Richard A. Cone, Justin Hanes

Journal of Controlled Release · 2014 · 311 citations · 46 references

DOI

Concepts

References

46

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

Malin Johansson, Mia Phillipson, Joel Petersson et al. · Proceedings of the National Academy of Sciences · 2008 · 2.2K citations · Full text

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A Dense Poly(Ethylene Glycol) Coating Improves Penetration of Large Polymeric Nanoparticles Within Brain Tissue

Elizabeth Nance, Graeme F. Woodworth, Kurt A. Sailor et al. · Science Translational Medicine · 2012 · 649 citations

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Size-Dependent Bioadhesion of Micro- and Nanoparticulate Carriers to the Inflamed Colonic Mucosa

Alf Lamprecht, Ulrich Schäfer, Claus‐Michael Lehr · Pharmaceutical Research · 2001 · 494 citations

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Biodegradable Nanoparticles for Targeted Drug Delivery in Treatment of Inflammatory Bowel Disease

Alf Lamprecht, Nathalie Ubrich, Hiromitsu Yamamoto et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 399 citations

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Comparative Uptake Studies of Bioadhesive and Non-Bioadhesive Nanoparticles in Human Intestinal Cell Lines and Rats: The Effect of Mucus on Particle Adsorption and Transport

Isabel Behrens, Ana Isabel Vila Pena, Marı́a José Alonso et al. · Pharmaceutical Research · 2002 · 369 citations

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