Concepedia

Homozygous deletion of CDKN2A (p16, p14) and CDKN2B (p15) genes is a poor prognostic factor in adult but not in childhood B-lineage acute lymphoblastic leukemia: a comparative deletion and hypermethylation study

Miyoung Kim, Seon‐Hee Yim, Nam-Sun Cho, Seong‐Ho Kang, Dae‐Hyun Ko, Bora Oh, Tae Young Kim, Hyun Jung Min, Cha Ja She, Hyoung Jin Kang,

Cancer Genetics and Cytogenetics · 2009 · 81 citations · 24 references

DOI

Concepts

References

24

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

, , +17

Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia.

Malcolm A. Smith, D Arthur, Bruce M. Camitta et al. · Journal of Clinical Oncology · 1996 · 916 citations

, , +13

Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies.

James G. Herman, Curt I. Civin, Jean‐Pierre J. Issa et al. · PubMed · 1997 · 410 citations

, , +17

p15INK4BCpG Island Methylation in Primary Acute Leukemia Is Heterogeneous and Suggests Density as a Critical Factor for Transcriptional Silencing

Elizabeth E. Cameron, Stephen B. Baylin, James G. Herman · Blood · 1999 · 230 citations

, , +17

Inactivation of p16 in Human Mammary Epithelial Cells by CpG Island Methylation

Scott A. Foster, David J. Wong, Michael T. Barrett et al. · Molecular and Cellular Biology · 1998 · 229 citations

, , +17