Biphasic Effect of HMG-CoA Reductase Inhibitor, Pitavastatin, on Vascular Endothelial Cells and Angiogenesis - Concepedia

Concepedia

Publication | Open Access

Biphasic Effect of HMG-CoA Reductase Inhibitor, Pitavastatin, on Vascular Endothelial Cells and Angiogenesis

DOI Full Paper Access

63

Citations

49

References

2005

Year

M. Katsumoto, Tetsuji Shingu, R. Kuwashima, Atsunori Nakata, Shuichi Nomura, Kazuaki Chayama

Circulation Journal

Abstract

Pitavastatin has a biphasic effect on HMVECs and on angiogenesis through at least 2 different pathways that include the mevalonate pathway.

References

	Year	Citations
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S) Anders Olsson, John J.V. McMurray, G Thorgeirsson, The Lancet Cardiovascular DiseaseHealth PolicyHyperlipidemiaDyslipidemiaPreventive Cardiology	1994	8.5K
The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol Levels Frank M. Sacks, Marc A. Pfeffer, Lemuel A. Moyé, New England Journal of Medicine	1996	7.5K
Prevention of Coronary Heart Disease with Pravastatin in Men with Hypercholesterolemia James Shepherd, Stuart M. Cobbe, Ian Ford, New England Journal of Medicine	1995	7.5K
Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol Levels New England Journal of Medicine	1998	5.3K
PREVENTION OF CORONARY HEART DISEASE WITH PRAVASTATIN IN MEN WITH HYPERCHOLESTEROLEMIA J Ames S Hepherd, S Tuart M. C Obbe, I An F Ord, Metabolic SyndromeCardiovascular EpidemiologyCardiovascular DiseaseCholesterol Lev- ElAtherosclerosis	1995	3.5K
Upregulation of Endothelial Nitric Oxide Synthase by HMG CoA Reductase Inhibitors Ulrich Laufs, Vito La Fata, Jorge Plutzky, Circulation	1998	1.8K
Antibodies to glutamic acid decarboxylase as predictors of insulin-dependent diabetes mellitus before clinical onset of disease J. Tuomilehto, Gabriele Vidgrén, L. Toivanen, The Lancet Metabolic SyndromeAutoimmune DiseaseInsulin-dependent Diabetes MellitusDiabetesImmunology	1994	1.7K
The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Yasuko Kureishi, Zhengyu Luo, Ichiro Shiojima, Nature Medicine AngiogenesisMolecular PhysiologyCardiovascular DiseaseCardiovascular Translational ResearchCell Signaling	2000	1.4K
Post-transcriptional Regulation of Endothelial Nitric Oxide Synthase mRNA Stability by Rho GTPase Ulrich Laufs, James K. Liao Journal of Biological Chemistry	1998	1K
Statins Have Biphasic Effects on Angiogenesis Michael Weis, Christopher Heeschen, Alec Glassford, Circulation	2002	681

Page 1