The effect of sildenafil on gastric emptying in patients with end-stage renal failure and symptoms of gastroparesis

Abstract

Sildenafil did not improve gastric emptying in patients with ESRF and gastric paresis. Sildenafil may have opposing effects on gastric peristalsis (causing gastric relaxation) compared with its effects on pyloric relaxation. Studies combining sildenafil with prokinetic drugs are of interest.