Effects on human thyroid function of sulphonamide and trimethoprim combination drugs.

Abstract

Changes in pain score and respiratory function after intrathecal injection of 4 mg morphine.Naloxone was given after the 12-hour observations.Hours after injection 0 4 12 16 24 44 Pain score* 8 0 0 0 0 8 Pao, (kPa) 6-8 10-2 7-7 10-3 F1o0 0-21 0-28 0-21 0-21 Paco2 (kPa) 7-25 6-62 6-25 4-63 Respiratory rate (breaths/min) 16 12 8 20 12 14 Heart rate (beats/min) 90 80 120 110 75 100 *0 = No pain; 10 = worst pain imaginable.Pao2 = Arterial oxygen pressure.F1o2 = Fractional inspired oxygen.Paco2 = Arterial carbon dioxide pressure.Conversion: SI to traditional units-Pao2 and Paco2: 1 kPa 7-5 mm Hg. CommentThis patient is unusual because she presented with severe osteomalacia, the hypercalcaemia being an unexpected observation.