Prolonged lactate clearance is associated with increased mortality in the surgical intensive care unit

Prospective Trial of Supranormal Values of Survivors as Therapeutic Goals in High-Risk Surgical Patients

William C. Shoemaker, Paul L. Appel, Harry B. Kram et al. · CHEST Journal · 1988 · 1.8K citations

Medicine, Perioperative Medicine, Surgery +11

A Randomized Clinical Trial of the Effect of Deliberate Perioperative Increase of Oxygen Delivery on Mortality in High-Risk Surgical Patients

Owen Boyd · JAMA · 1993 · 960 citations

Medicine, Perioperative Medicine, Surgery +14

Serum Cytokine Levels in Human Septic Shock

Michael R. Pinsky, Jean‐Louis Vincent, Jacques Devière et al. · CHEST Journal · 1993 · 888 citations

Veterinary Medicine, Immunology, Pathobiology +14

Serial blood lactate levels can predict the development of multiple organ failure following septic shock

Jan Bakker, P Gris, M Coffernils et al. · The American Journal of Surgery · 1996 · 856 citations

Veterinary Medicine, Critical Care Nursing, Physiology +16

Experimental and Clinical Studies on Lactate and Pyruvate as Indicators of the Severity of Acute Circulatory Failure (Shock)

Max Harry Weil, A. A. Afifi · Circulation · 1970 · 718 citations · Full text

Life Sciences, Physiology, Cellular Metabolism +12