In vivo measurement of noradrenaline in the locus coeruleus of rats during the formalin test: A microdialysis study

The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats

David Dubuisson, Stephen G. Dennis · Pain · 1977 · 2.5K citations

Medicine, Neuroscience, Pharmacology +17

The formalin test in mice: dissociation between inflammatory and non-inflammatory pain

Steinar Hunskaar, Kjell Hole · Pain · 1987 · 2.2K citations

Medicine, Anesthesiology, Pharmacology +17

Modified formalin test: characteristic biphasic pain response

Manabu Shibata, Tsuyako Ohkubo, Hiroshi Takahashi et al. · Pain · 1989 · 962 citations

Medicine, Anesthesiology, Pharmacology +16

Activation of locus coeruleus neurons by peripheral stimuli: Modulation by a collateral inhibitory mechanism

Jesse M. Cedarbaum, George K. Aghajanian · Life Sciences · 1978 · 380 citations

Life Sciences, Neurobiology, Neuroscience +9

Demonstration of two separate descending noradrenergic pathways to the rat spinal cord: Evidence for an intragriseal trajectory of locus coeruleus axons in the superficial layers of the dorsal horn

Jean‐Marc Fritschy, Reinhard Grzanna · The Journal of Comparative Neurology · 1990 · 171 citations

Life Sciences, Neurobiology, Neuroscience +17