High-performance liquid chromatographic-electrospray mass spectrometric determination of morphine and its 3- and 6-glucuronides: application to pharmacokinetic studies

Determination of morphine, morphine-3-glucuronide and (tentatively) morphine-6-glucuronide in plasma and urine using ion-pair high-performance liquid chromatography

Jan‐Olof Svensson, Anders Rane, Juliette Säwe et al. · Journal of Chromatography B Biomedical Sciences and Applications · 1982 · 278 citations

Pharmacy, Pharmacokinetics, Pharmacology +11

The analgesic activity of morphine‐6‐glucuronide.

Richard H. Osborne, P.I. Thompson, S Joel et al. · British Journal of Clinical Pharmacology · 1992 · 275 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Antinociceptive and ventilatory effects of the morphine metabolites: morphine-6-glucuronide and morphine-3-glucuronide

Qian-Ling Gong, Thomas Hedner, Jan Hedner et al. · European Journal of Pharmacology · 1991 · 178 citations

Medicine, Anesthesiology, Pharmacology +12

The pharmacologic effects of heroin in relationship to its rate of biotransformation.

E. L. Way, Jesse Kemp, Jennifer M. Young et al. · PubMed · 1960 · 141 citations

Pharmacy, Pharmacology, Toxicology +17

Isolation and Identification of Morphine 3- and 6-Glucuronides, Morphine 3,6-Diglucuronide, Morphine 3-Ethereal Sulfate, Normorphine, and Normorphine 6-Glucuronide as Morphine Metabolites in Humans

S.Y. Yeh, Charles W. Gorodetzky, H.A. Krebs · Journal of Pharmaceutical Sciences · 1977 · 138 citations

Medicine, Pharmacokinetics, Pharmacology +14