Tonic seizures of<scp>L</scp>ennox‐<scp>G</scp>astaut syndrome: Periictal single‐photon emission computed tomography suggests a corticopontine network

Abstract

This study suggests that the tonic seizures of LGS result from activity in a network, containing bilateral frontal and parietal association areas and the pons. We postulate that tonic seizures recruit the corticoreticular system, which connects frontal attentional areas to the pontine reticular formation, and is normally responsible for postural tone and orienting behavior.