Journal of Physics D Applied Physics · 2005 · 202 citations · 14 references
Public HealthDermatologyMaterials ScienceNanomaterialsRadiation ProtectionRadiation SafetyRadiation ResistanceSolar RadiationSun ProtectionSunburn PreventionUltraviolet Radiation ProtectionPhoton MigrationPhoton Migration ModelingSunscreen Action MechanismsSunscreen UseTape StrippingTitanium Dioxide NanoparticlesUltraviolet B ExposureUltraviolet Protection
Protecting human skin against harmful UV-B radiation coming from the sun is currently a problem. Due to the decreased thickness of the ozone layer, a more dangerous amount of UV-B light reaches the surface of our planet. This causes increased frequency of skin diseases. Titanium dioxide (TiO2) fine particles are embedded with sunscreens into the skin to effectively attenuate UV-B radiation. This study evaluates the most appropriate size of such particles assuming they are spheres. The distribution of TiO2 particles within the skin, achieved with topically applied sunscreens, is determined experimentally by the tape-stripping technique. Computer code implementing the Monte Carlo method is used to simulate photon migration within the plain 20??m thick horny layer matrix partially filled with nano-sized TiO2 particles. Dependences of harmful UV-B radiation of 307?311?nm absorbed by, backscattered from and transmitted through the horny layer on the concentration of TiO2 particles are obtained and analysed. As a result, particles of 62?nm are found to be the most effective in protecting skin against UV-B light.
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Variations of Hair Follicle Size and Distribution in Different Body Sites
Nina Otberg, Heike Richter, Hans Schaefer et al. · Journal of Investigative Dermatology · 2004 · 443 citations · Full text
Medicine, Anatomy, Dermatology +14