Glucose-dependent active ATP depletion by koningic acid kills high-glycolytic cells

On the Origin of Cancer Cells

Otto Warbürg · Science · 1956 · 13.3K citations

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

G L Wang, Bing‐Hua Jiang, E A Rue et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

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Hypoxia-inducible Factor 1 Activation by Aerobic Glycolysis Implicates the Warburg Effect in Carcinogenesis

Huasheng Lu, Robert A. Forbes, Ajay Verma · Journal of Biological Chemistry · 2002 · 837 citations · Full text

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2-Deoxy-<scp>d</scp>-glucose Increases the Efficacy of Adriamycin and Paclitaxel in Human Osteosarcoma and Non-Small Cell Lung Cancers <b> <i>In Vivo</i> </b>

Gregory Maschek, Niramol Savaraj, Waldemar Priebe et al. · Cancer Research · 2004 · 444 citations

Medicine, Oncology, Pharmacology +17

Novel therapy for liver cancer: direct intraarterial injection of a potent inhibitor of ATP production.

J.F. Geschwind, Young Hee Ko, Michael Torbenson et al. · PubMed · 2002 · 257 citations

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