Fine Needle Aspiration Cytology, Histology and Immunohistochemistry of Anaplastic Large Cell Ki-1–Positive Lymphoma

Abstract

The fine needle aspiration biopsy findings confirmed that large cell anaplastic, Ki-1-positive lymphoma should be considered in the cytologic differential diagnosis of anaplastic tumor within a lymph node. The differential diagnosis may include anaplastic carcinoma, malignant melanoma, sarcoma, Hodgkin's disease and histiocytic lymphoma. Immunostaining of fine needle aspiration biopsy material or, preferably, of histologic tissue sections is necessary for confirmation of the diagnosis.