Synthesis of 1-Azaazulenes from Cycloheptatrienylmethyl Ketone <i>O</i>-Pentafluorobenzoyloximes by Palladium-Catalyzed Cyclization and Oxidation

Abstract

Abstract Various 1-azaazulenes are synthesized from cycloheptatrienylmethyl ketone O-pentafluorobenzoyloximes by treatment with a catalytic amount of Pd(dba)2–t-Bu3P (dba = dibenzylideneacetone) and triethylamine in the presence of MS 4A via alkylideneaminopalladium(II) intermediates generated by oxidative addition of the oximes to a Pd(0) complex.